Prof. Stéphane Palfi
En bref
Stéphane Palfi, MD., PhD, is a Professor of Neurosurgery and Head of the Neurosurgery Department at Henri Mondor Medical center, Paris University (UPEC) and Head of a research Team 14 INSERM IMRB 955. His interests are in developmental therapeutics for Parkinson disease, Huntington disease, Tremor, Dystonia, Psychiatric disorders. He has worked extensively in the area of electrical neuromodulation of the brain in movement disorders, gene therapy for Parkinson disease, cell grafting for Huntington and Parkinson disease as well as primate models of neurodegenerative disorders. Pr. Stéphane Palfi has published extensively on trophic factor and enzymes based gene therapy in Parkinson disease and Huntington disease. He is a principal investigator on numerous preclinical and clinical studies and has been involved in studies of many novel agents including implanted brain devices, optogenetic, Homeoprotein, trophic factors GDNF, CNTF and Dopamine Lentiviral vectors.
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Expérience Professionnelle
Head of INSERM Research unit Neurosciences
Depuis 2015
Biomedical Institute IMRB / UPEC
Head Neurosurgical department
Depuis 2013
Med. faculty / UPEC / H.Mondor Hospital / APHP institution
Clinical research director
Depuis 2013
Medical Faculty / Neurosciences Department (DHU) PePsy / UPEC / APHP
Formation
Research Habilitation
2006
University Paris 12
PhD - Neuroscience
1997
Paris 12 University
Neurosurgical Board
1997
Paris University 11
Publications
Severe Obsessive-Compulsive Disorder Secondary to Neurodegeneration With Brain Iron Accumulation: Complete Remission After Subthalamic Nuclei Deep Brain Stimulation.
2019
Biological psychiatry
Lire iciGene Therapy for Parkinson's Disease: Preclinical Evaluation of Optimally Configured TH:CH1 Fusion for Maximal Dopamine Synthesis.
2019
Molecular therapy. Methods & clinical development
Lire iciAdverse Event with the Use of Carmustine Wafers and Postoperative Radiochemotherapy for the Treatment of High-grade Glioma.
2018
Asian journal of neurosurgery
Lire iciAssociations professionnelles
Académie Française de Chirurgie
Member
International Parkinson & Movement Disorder Society
Member
Société française de chirurgie
Member