Prof. Julien Calderaro, Md, Phd

Pubmed Development of AI-based pathology biomarkers in gastrointestinal and liver cancer. Nature reviews. Gastroenterology & hepatology Read it here B cells are associated with survival and immunotherapy response in sarcoma. Nature Read it here Detection of microsatellite instability in a panel of solid tumours with the Idylla MSI Test using extracted DNA. Journal of clinical pathology Read it here Polyploidy spectrum: a new marker in HCC classification. Gut Read it here Adeno-associated virus in the liver: natural history and consequences in tumour development. Gut Read it here Intrahepatic immune changes after hepatitis c virus eradication by direct-acting antiviral therapy. Liver international : official journal of the International Association for the Study of the Liver Read it here BAP1 mutations define a homogeneous subgroup of hepatocellular carcinoma with fibrolamellar-like features and activated PKA. Journal of hepatology Read it here Recurrent chromosomal rearrangements of <i>ROS1</i>, <i>FRK</i> and <i>IL6</i> activating JAK/STAT pathway in inflammatory hepatocellular adenomas. Gut Read it here Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma. Hepatology (Baltimore, Md.) Read it here Predicting survival after hepatocellular carcinoma resection using deep-learning on histological slides. Hepatology (Baltimore, Md.) Read it here Primary leiomyosarcoma of the liver: Two new cases and a systematic review. Annals of hepato-biliary-pancreatic surgery Read it here Multiphase Liver MRI for Identifying the Macrotrabecular-Massive Subtype of Hepatocellular Carcinoma. Radiology Read it here Early Hepatic Lesions Display Immature Tertiary Lymphoid Structures and Show Elevated Expression of Immune Inhibitory and Immunosuppressive Molecules. Clinical cancer research : an official journal of the American Association for Cancer Research Read it here Dual angiogenesis and PD-1 blockade in hepatocellular carcinoma. Hepatobiliary surgery and nutrition Read it here Corrigendum to: "BAP1 mutations define a homogeneous subgroup of hepatocellular carcinoma with fibrolamellar-like features and activated PKA" [J Hepatol (2020) 1-13]. Journal of hepatology Read it here BRAF-associated bile duct adenomatosis: a new entity? Histopathology Read it here Hepatobiliary MR contrast agent uptake as a predictive biomarker of aggressive features on pathology and reduced recurrence-free survival in resectable hepatocellular carcinoma: comparison with dual-tracer 18F-FDG and 18F-FCH PET/CT. European radiology Read it here Liver Resection for Solitary Transplantable Hepatocellular Carcinoma: The Role of AFP-Score. World journal of surgery Read it here Intra-tumoral tertiary lymphoid structures are associated with a low risk of early recurrence of hepatocellular carcinoma. Journal of hepatology Read it here PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases. International journal of cancer Read it here PD-L1 Expression and CD8⁺ T-cell Infiltrate are Associated with Clinical Progression in Patients with Node-positive Prostate Cancer. European urology focus Read it here A 17-Beta-Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease. Hepatology (Baltimore, Md.) Read it here Iso- or hyperintensity of hepatocellular adenomas on hepatobiliary phase does not always correspond to hepatospecific contrast-agent uptake: importance for tumor subtyping. European radiology Read it here Analysis of Liver Cancer Cell Lines Identifies Agents With Likely Efficacy Against Hepatocellular Carcinoma and Markers of Response. Gastroenterology Read it here <i>APC</i> germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures. Oncoimmunology Read it here Tertiary lymphoid structures in the era of cancer immunotherapy. Nature reviews. Cancer Read it here Hepatocellular Carcinomas With Mutational Activation of Beta-Catenin Require Choline and Can Be Detected by Positron Emission Tomography. Gastroenterology Read it here Molecular and histological correlations in liver cancer. Journal of hepatology Read it here Small-Molecule Inhibitors of Cyclophilins Block Opening of the Mitochondrial Permeability Transition Pore and Protect Mice From Hepatic Ischemia/Reperfusion Injury. Gastroenterology Read it here ESM1 as a Marker of Macrotrabecular-Massive Hepatocellular Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research Read it here Acute Biliary Obstruction after Transarterial Radioembolization with Yttrium-90. Journal of vascular and interventional radiology : JVIR Read it here Angiogenesis and immune checkpoint inhibitors as therapies for hepatocellular carcinoma: current knowledge and future research directions. Journal for immunotherapy of cancer Read it here Positron emission tomography/computed tomography with 18F-fluorocholine improve tumor staging and treatment allocation in patients with hepatocellular carcinoma. Journal of hepatology Read it here Hepatitis B Virus Pregenomic RNA in Hepatocellular Carcinoma: A Nosological and Prognostic Determinant. Hepatology (Baltimore, Md.) Read it here Differentiating focal nodular hyperplasia from hepatocellular adenoma: Is hepatobiliary phase MRI (HBP-MRI) using linear gadolinium chelates always useful? Abdominal radiology (New York) Read it here Correction to: Differentiating focal nodular hyperplasia from hepatocellular adenoma: Is hepatobiliary phase MRI (HBP-MRI) using linear gadolinium chelates always useful? Abdominal radiology (New York) Read it here Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma. Hepatology (Baltimore, Md.) Read it here Macrotrabecular-massive hepatocellular carcinoma: A distinctive histological subtype with clinical relevance. Hepatology (Baltimore, Md.) Read it here Interleukins-17 and 27 promote liver regeneration by sequentially inducing progenitor cell expansion and differentiation. Hepatology communications Read it here Curative salvage liver transplantation in patients with cirrhosis and hepatocellular carcinoma: An intention-to-treat analysis. Hepatology (Baltimore, Md.) Read it here AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of β-catenin activation. Journal of hepatology Read it here Bevacizumab improves survival in patients with synchronous colorectal liver metastases provided the primary tumor is resected first. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico Read it here Quantitative correlation between uptake of Gd-BOPTA on hepatobiliary phase and tumor molecular features in patients with benign hepatocellular lesions. European radiology Read it here Polycystic kidney features of the renal pathology in glycogen storage disease type I: possible evolution to renal neoplasia. Journal of inherited metabolic disease Read it here Hepatic Iron Overload following Liver Transplantation from a C282Y/H63D Compound Heterozygous Donor. Case reports in hepatology Read it here Dietary exacerbation of metabolic stress leads to accelerated hepatic carcinogenesis in glycogen storage disease type Ia. Journal of hepatology Read it here Systemic AA Amyloidosis Caused by Inflammatory Hepatocellular Adenoma. The New England journal of medicine Read it here Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress. Nature communications Read it here Argininosuccinate synthase 1 and periportal gene expression in sonic hedgehog hepatocellular adenomas. Hepatology (Baltimore, Md.) Read it here An Oxygenated and Transportable Machine Perfusion System Fully Rescues Liver Grafts Exposed to Lethal Ischemic Damage in a Pig Model of DCD Liver Transplantation. Transplantation Read it here Impact of hepatobiliary phase liver MRI versus Contrast-Enhanced Ultrasound after an inconclusive extracellular gadolinium-based contrast-enhanced MRI for the diagnosis of benign hepatocellular tumors. Abdominal radiology (New York) Read it here Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation. Gastroenterology Read it here Germline and somatic DICER1 mutations in familial and sporadic liver tumors. Journal of hepatology Read it here Prediction of hepatocellular carcinoma recurrence after liver transplantation: Comparison of four explant-based prognostic models. Liver international : official journal of the International Association for the Study of the Liver Read it here Contribution of Ultra Deep Sequencing in the Clinical Diagnosis of a New Fungal Pathogen Species: <i>Basidiobolus meristosporus</i>. Frontiers in microbiology Read it here A phosphokinome-based screen uncovers new drug synergies for cancer driven by liver-specific gain of nononcogenic receptor tyrosine kinases. Hepatology (Baltimore, Md.) Read it here PD-L1 expression in perihilar and intrahepatic cholangiocarcinoma. Oncotarget Read it here Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification. Journal of hepatology Read it here Sorafenib vs surgical resection for hepatocellular carcinoma with macrovascular invasion: A propensity score analysis. Liver international : official journal of the International Association for the Study of the Liver Read it here Renal Medullary Carcinoma: Establishing Standards in Practice. Journal of oncology practice Read it here Reply. Hepatology (Baltimore, Md.) Read it here Impact of time to surgery in the outcome of patients with liver resection for BCLC 0-A stage hepatocellular carcinoma. Journal of hepatology Read it here Delayed and short course of rapamycin prevents organ rejection after allogeneic liver transplantation in rats. World journal of gastroenterology Read it here Reply. Hepatology (Baltimore, Md.) Read it here Balanced Translocations Disrupting SMARCB1 Are Hallmark Recurrent Genetic Alterations in Renal Medullary Carcinomas. European urology Read it here Inflammatory hepatocellular adenomas developed in the setting of chronic liver disease and cirrhosis. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Read it here Minimally invasive surgery versus percutaneous radio frequency ablation for the treatment of single small (≤3 cm) hepatocellular carcinoma: a case-control study. Surgical endoscopy Read it here AAV2 and Hepatocellular Carcinoma. Human gene therapy Read it here An Unusual Cause of Cholecystitis. Gastroenterology Read it here Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV. Molecular therapy : the journal of the American Society of Gene Therapy Read it here Ultrasonography of gallbladder abnormalities due to schistosomiasis. Parasitology research Read it here Genotype-phenotype correlation of CTNNB1 mutations reveals different ß-catenin activity associated with liver tumor progression. Hepatology (Baltimore, Md.) Read it here Programmed death ligand 1 expression in hepatocellular carcinoma: Relationship With clinical and pathological features. Hepatology (Baltimore, Md.) Read it here Solitary splenic metastasis from nasopharyngeal carcinoma: a case report and systematic review of the literature. World journal of surgical oncology Read it here Primary Tumor Versus Liver-First Strategy in Patients with Stage IVA Colorectal Cancer: A Propensity Score Analysis of Long-term Outcomes and Recurrence Pattern. Annals of surgical oncology Read it here Role of Sorafenib in Patients With Recurrent Hepatocellular Carcinoma After Liver Transplantation. Progress in transplantation (Aliso Viejo, Calif.) Read it here Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets. Nature genetics Read it here BRAF V600E mutations in bile duct adenomas. Hepatology (Baltimore, Md.) Read it here Integration of tumour and viral genomic characterizations in HBV-related hepatocellular carcinomas. Gut Read it here Differentiation of focal nodular hyperplasia from hepatocellular adenomas with low-mechanical-index contrast-enhanced sonography (CEUS): effect of size on diagnostic confidence. European radiology Read it here Bile duct adenoma should not be designated as a reactive process. Pathology international Read it here BRAF V600E mutational status in bile duct adenomas and hamartomas. Histopathology Read it here Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver. Oncotarget Read it here Differentiation of focal nodular hyperplasia from hepatocellular adenoma: Role of the quantitative analysis of gadobenate dimeglumine-enhanced hepatobiliary phase MRI. Journal of magnetic resonance imaging : JMRI Read it here Hepatectomy for hepatocellular carcinoma larger than 10 cm: preoperative risk stratification to prevent futile surgery. HPB : the official journal of the International Hepato Pancreato Biliary Association Read it here Hepatocellular nodules expressing markers of hepatocellular adenomas in Budd-Chiari syndrome and other rare hepatic vascular disorders. Journal of hepatology Read it here Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas. Nature genetics Read it here Young investigator challenge: Cytomorphologic analysis of cerebrospinal fluid in 70 pediatric patients with medulloblastoma and review of the literature focusing on novel diagnostic and prognostic tests. Cancer cytopathology Read it here Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis. Hepatology (Baltimore, Md.) Read it here Greening the work force in Brazilian hotels: the role of environmental training. Work (Reading, Mass.) Read it here Open and laparoscopic resection of hepatocellular adenoma: trends over 23 years at a specialist hepatobiliary unit. HPB : the official journal of the International Hepato Pancreato Biliary Association Read it here Imaging strategies before beginning treatment of colorectal liver metastases. Diagnostic and interventional imaging Read it here Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation. Cancer cell Read it here Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy. Kidney international Read it here Hepatocellular carcinoma and nodular regenerative hyperplasia after chemotherapy for metastatic colorectal carcinoma. Hepatology (Baltimore, Md.) Read it here ALDH3A1 is overexpressed in a subset of hepatocellular carcinoma characterised by activation of the Wnt/ß-catenin pathway. Virchows Archiv : an international journal of pathology Read it here PI3K/AKT pathway activation in bladder carcinogenesis. International journal of cancer Read it here Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma. Oncoimmunology Read it here