Thierry Jacques De Baère, is head of the Interventional Radiology Unit at Institut Gustave Roussy Cancer Center in Villejuif, France, where he has worked since 1991. Gustave Roussy is the margest eropean cancer center. His clinical work is dedicated to minimal invasive therapy for treatment of liver, lung, and kidney tumors, including intra-arterial therapies for primary and secondary liver tumors, percutaneous ablation of liver tumors and lung tumor including radiofrequency and cryoabalation. He and his team have also investigated preoperative portal vein embolization in order to hypertrophy unembolized parts of the liver, as well as SIRT. IO4IO (interventional radiology for Immuno-oncology) is part of his new very active research fields. Many treatments, today in clinical routine, have been developed from experimental studies in order to allow a rapid transfer from bench-top to clinical applications. He is the author of 280 peer-reviewed articles and over 350 scientific communications, reveiwer for many cancer and interventional radiology journals, and section chief editor for oncology section in cardiovascular interventional radiology Journal. Member of CIRSE and ESMO. He is principal Investigator of several international studies on ablation, intraarterial therapies, combined therapies and other innovative locoregional treatments.