Professor René Adam is president of the Medical Board of the Paul Brousse Hospital, Villejuif, France and head of the Oncological Surgery Unit of the Hepato Biliary Center. Since 1994, he has held the position of professor of surgery at the Faculty of Medicine Kremlin Bicêtre at Paris South University, Paris. Professor Adam’s main fields of activity and research are surgery of the liver, biliary tract and pancreas, and hepatic transplantation. He is particularly involved in the treatment of hepatocellular carcinoma and of liver metastases. He has delivered more than 600 lectures on his research interests around the world, and has more than 200 publications in peer-reviewed journals.
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Villejuif, France
Surgeon & Head of Hepatobiliary Dept. Paul Brousse Hospital, Villzjuif, France
French
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English
Videos
Work Experience
Head of DepartmentDepartment of Hepatic Biliary Surgery, Cancer & Transplantation
Since 2012
Paul Brousse Hospital, Villejuif, France
Professor, Surgery
Since 1994
Kremlin Bicêtre Medical School,- Paris-Sud University, France
Research DirectorUnité Mixte de Recherche U935
Paris-Sud University, INSERM, France
Education
Fellowship, Surgery
1988
Paris-Sud University Medical School, Paris, France
Senior Resident
1986
Paris-Sud University Medical School, Paris, France
MD
1985
Paris-Sud University Medical School, Paris, France
Pubmed
Predictive model for microvascular invasion of hepatocellular carcinoma among candidates for either hepatic resection or liver transplantation.
2019
Surgery
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Chronological occurrence of PI3KCA mutations in breast cancer liver metastases after repeat partial liver resection.
2019
BMC cancer
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Late hepaticartery thrombosis after liver transplantation: which strategy? A single-center retrospective study.
2019
Transplant international : official journal of the European Society for Organ Transplantation
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Professional Associations
European Liver Transplant RegistryChairTreasurer of the European Surgical Association (ESA)General SecretaryEuropean Liver and Intestine Transplant Association (ELITA)Board Member
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Get updatedReceive the latest news from Prof. René Adam, MD, PHD
PubmedPredictive model for microvascular invasion of hepatocellular carcinoma among candidates for either hepatic resection or liver transplantation.
2019
Surgery
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Chronological occurrence of PI3KCA mutations in breast cancer liver metastases after repeat partial liver resection.
2019
BMC cancer
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Late hepaticartery thrombosis after liver transplantation: which strategy? A single-center retrospective study.
2019
Transplant international : official journal of the European Society for Organ Transplantation
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Trends in liver transplantation for primary biliary cholangitis in Europe over the past three decades.
2019
Alimentary pharmacology & therapeutics
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Evaluation of a micro-spectrometer for the real-time assessment of liver graft with mild-to-moderate macrosteatosis: A proof of concept study.
2019
Journal of hepatology
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Indocyanine green fluorescence imaging to evaluate graft perfusion during liver transplantation.
2019
HPB : the official journal of the International Hepato Pancreato Biliary Association
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Survival of children after liver transplantation for hepatocellular carcinoma.
2018
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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Left-liver Adult-to-Adult Living Donor Liver Transplantation: Can It Be Improved? A Retrospective Multicenter European Study.
2018
Annals of surgery
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[Late and sustained intraocular pressure elevation related to intravitreal anti-VEGF injections: Cases requiring filtering surgery (French translation of the article)].
2018
Journal francais d'ophtalmologie
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2018 Annual Report of the European Liver Transplant Registry (ELTR) - 50-year evolution of liver transplantation.
2018
Transplant international : official journal of the European Society for Organ Transplantation
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Late and sustained intraocular pressure elevation related to intravitreal anti-VEGF injections: Cases requiring filtering surgery.
2018
Journal francais d'ophtalmologie
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[Boston Keratoprosthesis with temporal aponeurosis graft: A solution when there seems to be no more].
2018
Journal francais d'ophtalmologie
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Predictive Factors for Survival in Children Receiving Liver Transplants for Wilson's Disease: A Cohort Study Using European Liver Transplant Registry Data.
2018
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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Arterial Lactate Concentration at the End of Liver Transplantation is an Early Predictor of Primary Graft Dysfunction.
2018
Annals of surgery
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Impact of DAAs on liver transplantation: Major effects on the evolution of indications and results. An ELITA study based on the ELTR registry.
2018
Journal of hepatology
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Locoregional treatments before liver transplantation for hepatocellular carcinoma: a study from the European Liver Transplant Registry.
2018
Transplant international : official journal of the European Society for Organ Transplantation
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Natural history of portal vein embolization before liver resection: a 23-year analysis of intention-to-treat results.
2018
Surgery
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Outcomes of left split graft transplantation in Europe: report from the European Liver Transplant Registry.
2018
Transplant international : official journal of the European Society for Organ Transplantation
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Totally intra-corporeal Pringle maneuver during laparoscopic liver resection.
2018
HPB : the official journal of the International Hepato Pancreato Biliary Association
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Vascular invasion and survival after liver transplantation for hepatocellular carcinoma: a study from the European Liver Transplant Registry.
2018
HPB : the official journal of the International Hepato Pancreato Biliary Association
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Suitability of livers for transplantation when treated by normothermic machine perfusion.
2018
Clinical transplantation
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Graft Protection Against Cold Ischemia Preservation: An Institute George Lopez 1 and Histidine-tryptophan-ketoglutarate Solution Appraisal.
2018
Transplantation proceedings
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A Systematic Review and Meta-Analysis of Cold In Situ Perfusion and Preservation of the Hepatic Allograft: Working Toward a Unified Approach.
2018
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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Mounier-Kuhn syndrome: a case of tracheal smooth muscle remodeling.
2017
Clinical case reports
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Editorial: A Matter of Bottom-Up or Top-Down Processes: The Role of Attention in Multisensory Integration.
2017
Frontiers in integrative neuroscience
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GSK3β and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation.
2017
International journal of molecular sciences
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Bilateral orbital lymphoma presenting as recurrence of orbital fat pad after blepharoplasty.
2017
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
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Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.
2017
American journal of respiratory and critical care medicine
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Hepatic Epithelioid Hemangioendothelioma and Adult Liver Transplantation: Proposal for a Prognostic Score Based on the Analysis of the ELTR-ELITA Registry.
2017
Transplantation
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MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer.
2017
Cancer research
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Liver Metastases From Breast Cancer: What Role for Surgery? Indications and Results.
2017
Clinical breast cancer
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A General and Highly Selective Cobalt-Catalyzed Hydrogenation of N-Heteroarenes under Mild Reaction Conditions.
2017
Angewandte Chemie (International ed. in English)
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Deletion of neuropilin 2 enhances detrusor contractility following bladder outlet obstruction.
2017
JCI insight
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Do patients' faces influence General Practitioners' cancer suspicions? A test of automatic processing of sociodemographic information.
2017
PloS one
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Evaluation of HTK Preservation Solutions in Liver Transplantation: A Long-Term Propensity-Based Analysis of Outcome From the European Liver Transplant Registry.
2017
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
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High Concomitant Misuse of Fentanyl in Subjects on Opioid Maintenance Treatment.
2017
Substance use & misuse
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Long-term outcomes of radiofrequency ablation combined with hepatectomy compared with hepatectomy alone for colorectal liver metastases.
2017
The British journal of surgery
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[Ocular graft-versus-host disease: An often misdiagnosed etiology of dry eye syndrome].
2017
Journal francais d'ophtalmologie
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Outcomes of surgical shunts and transjugular intrahepatic portasystemic stent shunts for complicated portal hypertension.
2017
The British journal of surgery
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Low-Temperature Hydrogenation of Carbon Dioxide to Methanol with a Homogeneous Cobalt Catalyst.
2017
Angewandte Chemie (International ed. in English)
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Selective Hydrogenation of Nitriles to Primary Amines by using a Cobalt Phosphine Catalyst.
2017
ChemSusChem
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Prediction of the Total Liver Weight using anthropological clinical parameters: does complexity result in better accuracy?
2017
HPB : the official journal of the International Hepato Pancreato Biliary Association
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Survival after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) for advanced colorectal liver metastases: A case-matched comparison with palliative systemic therapy.
2017
Surgery
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Can patient-reported measurements of pain be used to improve cancer pain management? A systematic review and meta-analysis.
2017
BMJ supportive & palliative care
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Predictive Profile-Nomogram for Liver Resection for Breast Cancer Metastases: An Aggressive Approach with Promising Results.
2017
Annals of surgical oncology
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Evaluation of the Novel Antichagasic Activity of [1,2,3]Triazolo[1,5-a]pyridine Derivatives.
2017
Current topics in medicinal chemistry
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The Cytotoxicity and Genotoxicity of Particulate and Soluble Cobalt in Human Urothelial Cells.
2017
Biological trace element research
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Inosine attenuates spontaneous activity in the rat neurogenic bladder through an A<sub>2B</sub> pathway.
2017
Scientific reports
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Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair.
2017
Stem cell reports
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Does emergency presentation of cancer represent poor performance in primary care? Insights from a novel analysis of linked primary and secondary care data.
2017
British journal of cancer
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Margin Status is Still an Important Prognostic Factor in Hepatectomies for Colorectal Liver Metastases: A Propensity Score Matching Analysis.
2017
World journal of surgery
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Hepatobiliary scintigraphy to evaluate liver function in associating liver partition and portal vein ligation for staged hepatectomy: Liver volume overestimates liver function.
2017
Surgery
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Increased survival means increasing roles for primary care after cancer diagnosis.
2017
The British journal of general practice : the journal of the Royal College of General Practitioners
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Extreme large-for-size syndrome after adult liver transplantation: A model for predicting a potentially lethal complication.
2017
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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Risk Adjustment in ALPPS Is Associated With a Dramatic Decrease in Early Mortality and Morbidity.
2017
Annals of surgery
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Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).
2017
British journal of cancer
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Impact of Surgical Treatment for Recurrence After 2-Stage Hepatectomy for Colorectal Liver Metastases, on Patient Outcome.
2017
Annals of surgery
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Prospective validation of transient elastography for staging liver fibrosis in patients undergoing hepatectomy and liver transplantation.
2017
Journal of hepatology
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Neoadjuvant chemotherapy for initially unresectable intrahepatic cholangiocarcinoma.
2017
The British journal of surgery
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CF airway smooth muscle transcriptome reveals a role for PYK2.
2017
JCI insight
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Defining Benchmarks in Liver Transplantation: A Multicenter Outcome Analysis Determining Best Achievable Results.
2017
Annals of surgery
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The role of cetuximab in converting initially unresectable colorectal cancer liver metastases for resection.
2017
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs.
2017
Critical care medicine
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Feasibility, safety and efficacy of two-stage hepatectomy for bilobar liver metastases of colorectal cancer: a LiverMetSurvey analysis.
2017
HPB : the official journal of the International Hepato Pancreato Biliary Association
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Unprecedented selective homogeneous cobalt-catalysed reductive alkoxylation of cyclic imides under mild conditions.
2017
Chemical science
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Comment on "Long-Term Survival Benefit and Potential for Cure after R1 Resection for Colorectal Liver Metastases": A Reply.
2017
Annals of surgical oncology
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Is Routine Intraoperative Contrast-Enhanced Ultrasonography Useful During Whole Liver Transplantation?
2017
World journal of surgery
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Onset of labour epidural analgesia with low-dose bupivacaine and different doses of fentanyl.
2017
Anaesthesia
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The Relevance of the UPS in Fatty Liver Graft Preservation: A New Approach for IGL-1 and HTK Solutions.
2017
International journal of molecular sciences
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Dosing time dependent in vitro pharmacodynamics of Everolimus despite a defective circadian clock.
2017
Cell cycle (Georgetown, Tex.)
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Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial.
2017
The Lancet. Oncology
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So pretty! The neural correlates of self-other vs familiar-other attractiveness comparisons.
2017
Social neuroscience
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[Macular ischemia in Waldenstrom's macroglobulinemia].
2017
Journal francais d'ophtalmologie
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Risk score to predict biliary leakage after elective liver resection.
2017
The British journal of surgery
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Cobalt-catalysed reductive C-H alkylation of indoles using carboxylic acids and molecular hydrogen.
2017
Chemical science
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Long-term outcomes of patients with 10 or more colorectal liver metastases.
2017
British journal of cancer
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Recurrence of hepatocellular carcinoma after liver transplantation: Is there a place for resection?
2017
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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Liver stiffness measurement by transient elastography predicts late posthepatectomy outcomes in patients undergoing resection for hepatocellular carcinoma.
2017
Surgery
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The role of atypical antipsychotics in sexuality: Road to recovery in schizophrenia.
2017
Current drug targets
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Relevance of proteolysis and proteasome activation in fatty liver graft preservation: An Institut Georges Lopez-1 <i>vs</i> University of Wisconsin appraisal.
2017
World journal of gastroenterology
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Try To Remember: Interplay Between Memory And Substance Use Disorder.
2017
Current drug targets
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Postnatal airway growth in cystic fibrosis piglets.
2017
Journal of applied physiology (Bethesda, Md. : 1985)
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Diffusion-weighted tractography in the common marmoset monkey at 9.4T.
2017
Journal of neurophysiology
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Sorafenib vs surgical resection for hepatocellular carcinoma with macrovascular invasion: A propensity score analysis.
2017
Liver international : official journal of the International Association for the Study of the Liver
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What are the current challenges of managing cancer pain and could digital technologies help?
2017
BMJ supportive & palliative care
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Liver transplantation for colorectal liver metastasis: Survival without recurrence can be achieved.
2017
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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Prognostic role of telomere length in malignancies: A meta-analysis and meta-regression.
2017
Experimental and molecular pathology
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Cross-Talk Between Sirtuin 1 and High-Mobility Box 1 in Steatotic Liver Graft Preservation.
2017
Transplantation proceedings
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Is Cure Possible After Sequential Resection of Hepatic and Pulmonary Metastases From Colorectal Cancer?
2017
Clinical colorectal cancer
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Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.
2017
Cell
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Outcomes of parenchyma-preserving hepatectomy and right hepatectomy for solitary small colorectal liver metastasis: A LiverMetSurvey study.
2017
Surgery
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Management of the Open Abdomen after Liver Transplantation.
2017
World journal of surgery
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Variables affecting maximum urethral closure pressure (MUCP) and abdominal leak point pressure (ALPP) measurements.
2017
International urogynecology journal
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Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices.
2017
Cell
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Resection of colorectal liver metastases after second-line chemotherapy: is it worthwhile? A LiverMetSurvey analysis of 6415 patients.
2017
European journal of cancer (Oxford, England : 1990)
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Human Norovirus Evolution in a Chronically Infected Host.
2017
mSphere
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Band structure evolution during the ultrafast ferromagnetic-paramagnetic phase transition in cobalt.
2017
Science advances
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Potential of a cure in patients with colorectal liver metastases and concomitant extrahepatic disease.
2017
Journal of surgical oncology
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Is there a role for microRNAs as novel predictors of prognosis in myocardial infarction?
2016
Annals of translational medicine
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Quality of life 10 years after liver transplantation: The impact of graft histology.
2016
World journal of transplantation
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Spatial coherence determination from the Fourier analysis of a resonant soft X-ray magnetic speckle pattern.
2016
Optics express
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Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice.
2016
PloS one
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Polyethylene glycols: An effective strategy for limiting liver ischemia reperfusion injury.
2016
World journal of gastroenterology
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Inflammation and Lymphedema Are Exacerbated and Prolonged by Neuropilin 2 Deficiency.
2016
The American journal of pathology
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Costs associated with instrument sterilization in gynecologic surgery.
2016
American journal of obstetrics and gynecology
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Liver Transplantation for Hepatic Trauma: A Study From the European Liver Transplant Registry.
2016
Transplantation
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Early tumour response as a survival predictor in previously- treated patients receiving triplet hepatic artery infusion and intravenous cetuximab for unresectable liver metastases from wild-type KRAS colorectal cancer.
2016
European journal of cancer (Oxford, England : 1990)
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Central Hepatectomy versus Extended Hepatectomy for Malignant Tumors: A Propensity Score Analysis of Postoperative Complications.
2016
World journal of surgery
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Erratum: Magnetic measurements with atomic-plane resolution.
2016
Nature communications
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Neutral oligosaccharides in feces of breastfed and formula-fed infants at different ages.
2016
Glycobiology
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Parenchymal-sparing hepatectomies (PSH) for bilobar colorectal liver metastases are associated with a lower morbidity and similar oncological results: a propensity score matching analysis.
2016
HPB : the official journal of the International Hepato Pancreato Biliary Association
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Esters, Including Triglycerides, and Hydrogen as Feedstocks for the Ruthenium-Catalyzed Direct N-Alkylation of Amines.
2016
Angewandte Chemie (International ed. in English)
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Magnetic measurements with atomic-plane resolution.
2016
Nature communications
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Outcomes of Rehepatectomy for Colorectal Liver Metastases: A Contemporary Multi-Institutional Analysis from the French Surgical Association Database.
2016
Annals of surgical oncology
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HEPATIC EPITHELIOID HEMANGIO-ENDOTHELIOMA AND ADULT LIVER TRANSPLANTATION: PROPOSAL FOR A PROGNOSTIC SCORE BASED ON THE ANALYSIS OF THE ELTR-ELITA REGISTRY.
2016
Transplantation
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PARAGON II - A single arm multicentre phase II study of neoadjuvant therapy using irinotecan bead in patients with resectable liver metastases from colorectal cancer.
2016
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Surgery of Colorectal Liver Metastases: Pushing the Limits.
2016
Liver cancer
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A Novel Imaging Marker for Small Vessel Disease Based on Skeletonization of White Matter Tracts and Diffusion Histograms.
2016
Annals of neurology
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Outcome after associating liver partition and portal vein ligation for staged hepatectomy and conventional two-stage hepatectomy for colorectal liver metastases.
2016
The British journal of surgery
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Chromoendoscopy in combination with random biopsies does not improve detection of gastric cancer foci in CDH1 mutation positive patients.
2016
Endoscopy international open
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Prophylactic total gastrectomy in the management of hereditary tumor syndromes.
2016
International journal of colorectal disease
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Specialty-Specific Operative Units Promote Cost-Effectiveness and Patient Safety.
Professional AssociationsEuropean Liver Transplant RegistryChairTreasurer of the European Surgical Association (ESA)General SecretaryEuropean Liver and Intestine Transplant Association (ELITA)Board MemberFrench Association of Surgery.Board MemberResearch committee of the IHPBA (International Hepatic, Pancreatic and Biliary Association)ChairFrench association of HPB SurgeryPast-PresidentAmerican Society of Clinical Oncology (ASCO)MemberEuropean Society of Surgical Oncology (ESSO)MemberEuropean Society of Organ Transplantation (ESOT)Member
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